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Translational Cores

Neuromusculoskeletal and Metabolic Metabolic, Neuromuscular, and Skeletal

The Metabolic, Neuromuscular, and Skeletal Core provides assessments specific to skeletal muscle contraction, architecture, volume and oxidative capacity. Bone density is measured along with dietary intake, total body

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Cardiovascular and Pulmonary

The Cardiovascular and Pulmonary Core provides state-of-the-art assessments specific to the heart, lungs and circulatory system. Studies to map the neural circuits that control blood pressure and lung function enable interventions such as spinal cord Epidural Stimulation (scES).

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Human Locomotion and Movement Performance Movement Performance and Locomotor Recovery

Movement Performance and Locomotor Recovery provides assessments of gait and stepping and guides development of optimal individualized programs of therapy and interventions for individuals with spinal cord injuries.

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VOP Bladder Urogenital and Bowel

The Urogenital and Bowel Core provides assessments of bladder, bowel, and sexual function in individuals with spinal cord injuries.

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Neuro-Physiology and Neuro-Imaging Neurophysiology

The Neurophysiology Core provides physiological motor and sensory assessments and performs magnetic resonance imaging that allow appropriate adjustments to therapeutic interventions.

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VOP-Engineering-Model Engineering

The Engineering Core designs and constructs therapeutic delivery systems, software and imaging systems as well as manages aspects of information technology and develops algorithms to mine KSCIRC data and provide analysis.

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Research Medical

Supports all surgical procedures and post-operative care; provides medical oversight during epidural stimulation and activity-based interventions; supports research medical procedures; management and processing of blood, urine and tissues sample for human and porcine; IRB and FDA regulatory.

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Biostatistics, Outcomes, Database, and Communications

Our Biostatistics and Outcomes Core is dedicated to the comprehensive analysis of the effectiveness of therapeutic interventions that individuals with spinal cord injury undergo. The results of such analyses are then used to inform the design of continued or subsequent therapeutic interventions. Using a collaborative approach within the Translational Research division of the Kentucky Spinal Cord Injury Research Center (KSCIRC) at the University of Louisville, the Biostatistics and Outcomes Core conducts research and support activities regarding the individual and collective outcomes related to Spinal Cord Injury (SCI) across the continuum of care and across the lifespan. This core analyzes how the health of individuals with SCI is affected in the real world based on their own reported experiences and detailed analyses of data coming from the KSCIRCScientific Cores as well as all relevant external data.The Database and Communications Division of this Core supports other cores with various aspects of data management including process analysis, data systems design and implementation, data integration and review, general reporting and analysis. Including the release of information through our web/print/social channels and the compiling of digital media.

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Regulatory

The Regulatory Core works closely with the University Human Subjects Protection Program Office (HSPPO) and ensures that all governmental, hospital, and university regulations and guidelines are followed for research and patient care.

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Finance and Administrative

The Finance and Administration Core is responsible for the fiscal and administrative oversight of the entire translational research program. This Core serves as liaison to internal University departments, granting agencies, and research partners to ensure overall coordination and facilitation of grant activities, budgeting, and contract negotiation and implementation.  Key Core activities include: internal and external communications, grant submission and maintenance, purchasing, account reconciliation, long-range financial planning, and financial reporting.

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Adult NeuroRecovery


Translational Cores

Metabolic, Neuromuscular, and Skeletal

Cardiovascular and Pulmonary

Movement Performance and Locomotor Recovery

Urogenital and Bowel

Neurophysiology

Engineering

Research Medical

Biostatistics and Outcomes

Database and Informatics

Regulatory

Finance and Administrative


Investigators