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Design, develop and construct devices, sensors, software, imaging systems, data management methodologies and systems, information technology, data analysis and interpretation, novel therapeutic delivery systems, etc. Develop and implement new algorithms to mine the data and identify patterns. Provide other related IT support to the research projects and other Cores. Partner with the program leadership team to assist in integrating the biomarker, electrophysiological, metabolic and clinical information acquired from this project with longitudinal data collected from the NACTN registry.